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July 18: MHRA Drug Safety Update: Parenteral amphotericin B: reminder of risk of potentially fatal adverse reaction if formulations confused

July 18 - MHRA Drug Safety Update: Eltrombopag (Revolade): reports of interference with bilirubin and creatinine test results

July 18 - MHRA Drug Safety Update: Pressurised metered dose inhalers (pMDI): risk of airway obstruction from aspiration of loose objects

July 18 - MHRA Drug Safety Update: Darunavir boosted with cobicistat: avoid use in pregnancy due to risk of treatment failure and maternal-to-child transmission of HIV-1

June 18 - MHRA Drug Safety Update: Dolutegravir (Tivicay▼, Triumeq▼, Juluca▼): signal of increased risk of neural tube defects; do not prescribe to women seeking to become pregnant ; exclude pregnancy before initiation and advise use of effective contraception. 

June 18 - MHRA Drug Safety Update:  Denosumab (Xgeva▼) for giant cell tumour of bone: risk of clinically significant hypercalcaemia following discontinuation

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The Buckinghamshire Formulary is a joint venture between Aylesbury Vale CCG, Buckinghamshire Healthcare NHS Trust and Chiltern CCG.  

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